WebApr 1, 2024 · Association tests. 1. Introduction. Genome-wide association studies (GWAS) detects common genetic variants that associate with complex disorders, with the ultimate goal of developing translational prevention or treatment strategies. The main biomarker under study is single nucleotide polymorphisms (SNPs) that usually consist of two alleles. WebNov 12, 2024 · Genome-wide association studies (GWAS), genetic surveys of the whole genome to detect variants associated with a trait in natural populations, are a powerful approach for dissecting complex …
Status and prospects of genome-wide association studies in plants …
WebPlatinum drugs combined with other agents have been the first-line treatment for non-small cell lung cancer (NSCLC) in the past decades. To better evaluate the efficacy of platinum–based chemotherapy in NSCLC, we establish a platinum chemotherapy response prediction model. Here, a total of 217 samples from Xiangya Hospital of Central South … WebFeb 10, 2024 · The long-term breeding history of L. edodes in China was analyzed using whole-genome information. Using GWAS analysis, three loci and two genes were identified that might be involved in the Cd accumulation of L. edodes. This study provides a valuable resource for future genetics and breeding studies for L. edodes. td smiles
GWAS Catalog - European Bioinformatics Institute
WebNational Center for Biotechnology Information WebFeb 18, 2024 · Here, the authors conduct GWAS of fruit quality and phenological traits in a panel of 312 sand pear accessions using SNPs called from resequencing data, and reveal the involvement of a lignin ... WebApr 11, 2024 · We conducted a GWAS for CIM with 2,010,300 SNVs, identifying a novel locus on canine chromosome 1 (P-val = 2.76 × 10−10). Associated SNVs are intergenic or intronic and are found in two clusters across a 1.7-Mb region. ... Cases were diagnosed by a veterinarian via a standard or barium contrast radiograph, history of clinical signs from ... td simulink