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Csnk2a1 cancer

WebSep 19, 2024 · Fusogenic peptide delivery of bioactive siRNAs targeting CSNK2A1 for treatment of ovarian cancer Mol Ther Nucleic Acids. 2024 Sep 19;30:95-111. doi: 10.1016/j.omtn.2024.09.012. eCollection 2024 Dec 13. Authors WebMar 10, 2024 · CSNK2A1 provided by HGNC Official Full Name casein kinase 2 alpha 1 provided by HGNC Primary source HGNC:HGNC:2457 AllianceGenome:HGNC:2457 RefSeq status Organism Lineage Also known as Summary Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein.

CSNK2A1 casein kinase 2 alpha 1 - NIH Genetic Testing Registry …

WebExpression of CSNK2A1 in cancer - Summary - The Human Protein Atlas CSNK2A1 PATHOLOGY CANCER ANTIBODIES AND VALIDATION Dictionary Human pathology PROGNOSTIC SUMMARYi Prognostic marker in liver cancer (unfavorable) Liver cancer p<0.001 RNA EXPRESSION OVERVIEWi TCGA dataseti RNA cancer category: Low … WebMiR-1184 directly targets CSNK2A1 via using RNA immunoprecipitation assay and luciferase reporter gene assay. According to the results, CSNK2A1 over-expression reversed the functions of miR-1184 over-expression in suppressing colon cancer cell proliferation and enhancing their apoptosis. billy the fridge rap song https://insegnedesign.com

Subcellular - CSNK2A1 - The Human Protein Atlas

WebFeb 5, 2024 · The promoter of the well-known CK2α, CSNK2A1, displays characteristics of a housekeeping gene, whereas CSNK2A3 has a characteristic of a regulated promoter with two TATA boxes and a CAAT box. GPR68, a family of the G protein-coupled receptors, is also known as ovarian cancer G protein-coupled receptor 1 (OGR1). WebApr 7, 2014 · We found that Csnk1a1 knockdown results in decreased Rps6 phosphorylation, increased p53 activity, and myeloid differentiation. Consistent with … WebCK2α/CSNK2A1 is involved in cancer progression by phosphorylating various signaling molecules. Considering the role of CSNK2A1 in cancer progression and the phosphorylation of SIRT6 and the role of SIRT6 in chemoresistance through the DNA damage repair pathway, CSNK2A1 and SIRT6 might be involved in resistance to … billy the fridge rap

An Integrative Pan-Cancer Analysis of the Prognostic and …

Category:Defining the KRAS-regulated kinome in KRAS-mutant …

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Csnk2a1 cancer

National Center for Biotechnology Information

WebJun 14, 2016 · The capacity of CSNK2 to promote cancer cell survival in vitro was also revealed in a recent large-scale screen via RNA interference knockdown and cDNA … WebApr 1, 2024 · Functionally crucial for cell development and commonly dysregulated in cancer, CSNK2 is a pleiotropic serine/threonine kinase encoded by two distinct catalytic …

Csnk2a1 cancer

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WebGene summary (Entrez)i. Useful information about the gene from Entrez. Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell … WebDec 2, 2024 · Stable cancer cell lines with CSNK2A1 gene overexpression or knockdown were established to investigate the function and mechanism of CSNK2A1 in GC cells. …

WebAccording to the results, CSNK2A1 over-expression reversed the functions of miR‐1184 over-expression in suppressing colon cancer cell proliferation and enhancing their apoptosis. WebDec 13, 2024 · CSNK2A1 is an oncogene found overexpressed in several cancer types, including ovarian cancer, and is responsible for increased growth and cell survivability in the presence of chemotherapeutic agents.27,28 The protein encoded by CSNK2A1, CK2α, plays a major role in cell cycle regulation, cell-cell communication, DNA repair activation, …

WebThis section gives an overview of CSNK2A1, along with links to any related data and resources. Census gene Curated gene Mouse gene Hallmark gene COSMIC gene CSNK2A1 (COSG646561) Genomic coordinates 20:472498..543835 (negative strand) Synonyms Cka1, Cka2, CCDS13003.1, ENSG00000101266.18, NM_001895.3, … WebGene view. The gene view histogram is a graphical view of mutations across CSNK2A1. These mutations are displayed at the amino acid level across the full length of the gene …

WebMar 21, 2024 · Entrez Gene Summary for CSNK2A1 Gene. Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is …

WebSep 30, 2024 · Cholangiocarcinoma (CCA), accounting for about 15% of primary liver cancer, is the second most prevalent cancer after hepatocellular carcinoma (HCC) [].CCA is a highly lethal malignancy in the biliary tree, and its incidence and mortality continue to increase [2,3].Currently, the prognosis of CCA is poor, with a 5-year overall survival (OS) … billy the fridge rapperbilly the fridge politicsWebNov 1, 2024 · Our computational analysis identifies casein kinase 2A1 (CSNK2A1) as a mediator of MEK/ERK inhibitor resistance in KRAS (G12C) mutant lung cancer cells. CSNK2A1 knockdown reduces cell proliferation, inhibits Wnt/β-catenin signalling and increases the anti-proliferative effect of MEK inhibition selectively in KRAS (G12C) … cynthia fouts gimbertWebJun 11, 2024 · Our results reveal that CSNK2A1-dependent HMGA2 phosphorylation may partially underlie cisplatin-resistance in cervical cancer, suggesting that HMGA2 phosphorylation may have potential as … cynthia fowler obituaryWebMay 17, 2024 · In fact, the analysis of human microarray data of pancreatic β-cell enriched samples from T2DM patients and healthy donors revealed a significant rise of ∼ 1.2-fold … cynthia fowler texasWebCSNK2A1. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a short form of the gene name, according to HGNC. Full gene name according to HGNC. cynthia fournierWebApr 8, 2024 · (A) Box plot of CSNK2A1 mRNA expression levels in multiple cancer types. In each case tumor samples are in red and normal samples are in black. Only tumor types with a statistically significant difference in expression between cancer and control samples ( P < 0.01 ) are shown. cynthia fournier toulouse