WebOct 11, 2024 · ATP-binding cassette (ABC) proteins were first shown to influence the accumulation of glucocorticoids in cells almost three decades ago, but observations over the past 10 years suggest that... WebJun 25, 2009 · ATP-binding cassette transporter (ABC)A1 lipidates apolipoprotein A-I both directly at the plasma membrane and also uses lipids from the late endosomal or lysosomal compartment in the internal lipidation of apolipoprotein A-I. However, how ABCA1 targeting to these specific membranes is regulated remains unknown. Palmitoylation is a …
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WebJul 22, 2024 · The heme-binding site captures heme from the membrane using a glutamate residue of either subunit as an axial ligand and sequesters the heme within the … WebJan 18, 2024 · Like all of Gray’s work, each piece is grounded in a design philosophy that draws on nature, the corporeal and organic phenomenon. Gray’s work is on display in … porch with storage
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WebJul 3, 2014 · The deduced 1,642-amino acid protein has a calculated molecular mass of 183 kD. It has up to 16 predicted transmembrane segments in 2 transmembrane domains, which are followed by their respective nucleotide-binding folds. Petry et al. (2003) also identified 2 alternatively-spliced ABCA5 transcripts, one of which encodes a 925-amino acid ABC ... WebOct 29, 2024 · ATP-binding cassette protein ABCF1 couples transcription and genome surveillance in embryonic stem cells through low-complexity domain Eun-Bee Choi, Munender Vodnala , Madeleine Zerbato, Jianing Wang, [...], and Yick W. Fong +3 authors Authors Info & Affiliations Science Advances 29 Oct 2024 Vol 7, Issue 44 DOI: … WebSep 25, 2024 · The role of the ATP binding cassette transporter A1 (ABCA1) in maintaining cellular lipid homeostasis in cardiovascular disease is well established. More recently, the important beneficial role played by ABCA1 in modulating pathogenic disease mechanisms, such as inflammation, in a broad range of chronic conditions has been … porch with sliding door